- A examine discovered that in each women and men, increased muscle mass was related to decrease mortality from heart problems (CVD).
- Increased physique fats was additionally related to decrease CVD mortality threat in females however not in males.
- The researchers declare that in females, constructing muscle mass could also be extra necessary than losing a few pounds for cardiovascular well being.
The researchers behind the examine be aware that over the previous 50 years, dying charges from CVD have fallen in each women and men in the USA.
Nonetheless, the speed of decline has been slower amongst females than males, and the speed of coronary heart assaults in females aged 35–54 years is definitely rising.
As well as, research means that despite the fact that females have a decrease incidence of CVD than males, they’ve the next mortality charge and worse prognosis after an acute cardiovascular occasion.
As CVD appears to have an effect on the sexes in a different way, there’s an pressing want to find out whether or not medical doctors ought to supply totally different recommendation about prevention to their female and male sufferers.
A brand new examine by researchers on the College of California, Los Angeles, means that the main focus for females ought to be on sustaining or rising muscle mass relatively than shedding fats.
The findings seem within the Journal of the American Heart Association.
The researchers analyzed physique composition information from the
The info got here from a complete of 5,627 females and 5,836 males, all aged over 20 years.
Based mostly on the info, the researchers break up the examine individuals into 4 teams:
- low muscle mass and low physique fats
- low muscle mass and excessive physique fats
- excessive muscle mass and low physique fats
- excessive muscle mass and excessive physique fats
In each sexes, the uncooked information confirmed that increased ranges of fats have been related to increased CVD mortality, no matter muscle mass.
Nonetheless, after accounting for different components which are recognized to have an effect on CVD mortality, the connection between physique fats and the chance of dying from CVD modified fully in females.
After making these changes, the researchers discovered that females with excessive physique fats and excessive muscle mass had a 42% decrease threat of dying from CVD in contrast with females who had a low muscle mass and low physique fats.
Against this, males with excessive muscle mass and excessive physique fats had a 26% lowered threat of dying from CVD in contrast with males with low measurements, whereas these with excessive muscle mass and low physique fats had a 60% decreased threat.
The researchers imagine that their examine helps the necessity for a shift within the focus of the recommendation that healthcare professionals give to females. This shift is towards rising muscle mass by bodily train and away from weight reduction.
“[I]t demonstrates the potential significance of recommendation to maximise muscle mass in girls. This diverges from the present emphasis on weight reduction in CVD prevention, and thus strategies to virtually obtain such physique composition alteration have to be additional evaluated.”
It’s value emphasizing that the obvious protecting impact of fats in females solely emerged after adjusting for different CVD threat components.
Amongst these CVD threat components have been:
- levels of cholesterol
- hypertension (hypertension)
- diabetes and prediabetes
- hormone substitute remedy (HRT)
There’s a extremely advanced interaction between physique fats and these different threat components. For instance,
Nonetheless, the authors be aware a number of believable methods wherein fats may present some safety to females.
As an illustration, they spotlight
Additionally they be aware that in premenopausal females, the physique shops about 50% of its fats simply beneath the pores and skin within the thighs and buttocks, whereas in males, the physique shops 98% of the whole fats extra deeply within the higher physique.
Throughout and after menopause in females, nevertheless, fats tissue begins to build up within the stomach, the place it’s related to elevated CVD threat.
The authors additionally be aware that in people of the identical age and weight, the feminine physique tends to build up fats by multiplying the variety of fats cells, whereas the male physique usually grows bigger fats cells.
Giant (“hypertrophied”) fats cells are related to detrimental metabolic penalties, they write.
The researchers acknowledge some limitations of their examine.
Firstly, the examine design didn’t enable them to show cause-and-effect relationships between muscle mass or fats mass and CVD mortality, solely associations.
As well as, they are saying that the method that they used to measure the physique composition of volunteers — referred to as “dual energy X‐ray absorptiometry” or DXA — can overestimate muscle mass in older folks and people who lead sedentary lives.