Two completely different therapy protocols have proved efficient for youngsters with kind 1 diabetes and younger individuals with kind 2 diabetes, in keeping with Sidra Medication’s Analysis Annual Report for 2020 printed on-line lately.
At Sidra medication, kind 1 diabetes is managed with glucose sensors and insulin pumps, whereas kids with kind 2 diabetes are actually being handled with a brand new medicine.
The analysis within the Division of Paediatric Endocrinology focuses on understanding the causes of diabetes mellitus and the early onset of weight problems in kids and creating new applied sciences in managing childhood diabetes.
“Over the past two years, now we have recognized each little one (from start to 18 years) with diabetes in Qatar and started to unravel the biochemical and genetic mechanisms that result in diabetes in all these kids,” stated Prof. Khalid Hussain, Division Chief of Paediatric Endocrinology Chair of Medical Training, in a report on Diabetes and Weight problems Analysis at Sidra Medication.
“We now know the causes of diabetes in each little one and have began implementing remedies based mostly on the underlying biochemical and genetic mechanisms, thus bringing precision medication into the scientific setting,” he stated.
In line with Prof. Hussain, analysis in childhood diabetes and weight problems is a nationwide precedence space for Qatar, and consequently, Sidra Medication’s analysis matches very properly with nationwide priorities.
Analysis at Sidra Medication has proven that Qatar has the fourth-highest incidence of childhood kind 1 diabetes mellitus on the planet.
“A few of these kids with kind 1 diabetes are actually managed with cutting-edge expertise (utilizing glucose sensors and insulin pumps), with Sidra Medication being a world chief on this expertise. This work is pushed by my colleague Dr. Goran Petrovski,” stated Prof. Hussain.
The protocol is predicated on the efficient use of an insulin pump. The pump, a hybrid closed-loop system, acts as a man-made pancreas to assist kids and younger individuals with T1D management their insulin dosage with out the necessity for a number of day by day injections. Based mostly on an initiation schedule developed in-house at Sidra Medication, the protocol additionally permits for distant follow-up care.
Additionally, kids with kind 2 diabetes are actually being handled with a brand new medicine (Liraglutide) which is anticipated to assist with weight reduction and management their blood glucose.
As well as, some sufferers have been in a position to cease the day by day insulin injections and have been placed on oral medicines.
“This has been fully transformational for these sufferers. In our weight problems analysis, now we have recognized kids with uncommon genetic causes of early-onset weight problems,” Prof. Hussain.
Highlighting an instance of precision medication, he stated, “A toddler introduced with extreme weight problems (28kg at 18 months). We discovered the genetic reason behind the weight problems, and he or she has now been handled with a medication tailor-made to the genetic defect.”
“Her weight is now 15kg after one 12 months of therapy. Her mother and father are delighted with the transformation in her life. She is now a totally regular wholesome little one,” stated Prof. Hussain.